SH-FAPI-4

P017
Grade:
GMP product
Tested for sterility and bacterial endotoxins
Description:
SH-FAPI-4 is a selective fibroblast activation protein (FAP) inhibitor from the FAPI family.
It is designed to accumulate specifically in FAP-positive tumors and interfere with the function of cancer-associated fibroblasts (CAFs) in the tumor microenvironment.
By inhibiting FAP activity, SH-FAPI-4 aims to slow tumor progression, enhance the effectiveness of other cancer therapies, and modulate the tumor environment.
Molar weight:
574.64 g/mol (net substance)
Molecular formula:
C₂₇H₃₂F₂N₆O₄S (net substance)
CAS №:
N/A
Retest date:
Not less than 18 months from the manufacturing date
Packaging:
2R/4ml or 8R/10ml Type I glass vials with bromobutyl rubber stoppers
Storage conditions:
–20 ±5 °C
Transportation at 2–8 °C (less than 1 month)
Available quantities:
0.1 mg; 1.0 mg; custom quantity upon request
Quality parameters

Quality parameters

Appearance: White solid
Identification:
– HPLC: Retention time of main peak corresponds to the SH-FAPI-4 reference standard
– Mass spectrometry: m/z = 574.6 ± 4
Residual heavy metals (ICP-OES): ≤ 100 ppm
Purity (HPLC): ≥ 98.0%
Bacterial endotoxins (gel-clot method): ≤ 10.0 EU/vial
Sterility (direct inoculation method): Sterile (passes test)
Sterility tests are performed for sterile products, made in aseptic conditions (class A).
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