L-HCT HCl

P025
Grade:
GMP product
Tested for bioburden and bacterial endotoxins
Description:
L-Homocysteine thiolactone is an amine-reactive compound used in the study of post-translational protein modification, especially at lysine residues.
It is an intramolecular thioester of homocysteine that prevents translational incorporation of homocysteine into proteins.
L-HCT HCl is also a synthetic PET radiotracer and has been used for imaging brain tumors and other cancers.
Synonyms:
L-Homocysteine thiolactone hydrochloride
Molar weight:
153.63 g/mol (net substance)
Molecular formula:
C₄H₇NOS · HCl (net substance)
CAS №:
31828-68-9
PubChem CID:
123139
Retest date:
Not less than 18 months from the manufacturing date
Packaging:
2R/4ml or 8R/10ml Type I glass vials with bromobutyl rubber stoppers
Storage conditions:
–20 ±5 °C
Transportation at 2–8 °C (less than 1 month)
Available quantities:
0.1 mg; 1.0 mg; custom quantity upon request
Quality parameters

Quality parameters

Appearance: White solid
Identification:
– HPLC: Retention time of main peak corresponds to that of L-HCT HCl reference standard
– Mass spectrometry: m/z = 135.2 ± 4
Residual heavy metals (ICP-OES): ≤ 100 ppm
Purity (HPLC): ≥ 98.0%
Bacterial endotoxins (gel-clot method): ≤ 10.0 EU/vial
Bioburden (microbial enumeration tests):
– TAMC ≤ 10² CFU/vial
– TYMC ≤ 10¹ CFU/vial
Bioburden tests are performed for non-sterile products.
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